ANALYSIS OF REGULATIONAL MECHANISM OF FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) EXPRESSION USING FSHR-GFP TRANSGENIC MEDAKA

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Aberrant expression of follicle stimulating hormone receptors (FSHR) in thyroid neoplasia

Introduction In normal conditions FSHR are expressed in the ovary and the testis. It is well known that they can also be expressed in gonadal tumours. However, recently we have found FSHR immunopositivity in tumoral tissues of other endocrine tumours, namely pituitary adenomas, adrenal tumours and neuroendocrine gut and lung tumours (carcinoids). The aim of this study was to see whether the sam...

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Expression of follicle stimulating hormone receptors (FSHR) in thyroid tumours – a marker of malignancy?

BACKGROUND In normal conditions FSHR are expressed in granulosa cells of the ovary and Sertoli cells of the testis. They can be expressed also in gonadal tumours. However, recently the expression of FSHR was found in tumoral cells and intra-tumoral blood vessels of many other tumours, including thyroid tumours. Aim of this study was to see whether the expression of FSHR can be useful in the dif...

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Immunohistochemical detection of follicle stimulating hormone receptor (FSHR) in neuroendocrine tumours.

INTRODUCTION Follicle stimulating hormone receptors (FSHR) are well known to be expressed in gonads and in gonadal tumours. Recently,their incidence has also been revealed in endocrine non-gonadal tumours such as adrenal and pituitary tumours. Moreover, FSHR immunostaininghas also been reported in endothelium of intra- and peritumoral blood vessels of a large series of cancers. The presentpaper...

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Follicle Stimulating Hormone Receptor (FSHR) Gene and Postmenopausal Epithelial Ovarian Cancer (EOC)

Objective: Follicle stimulating hormone receptor (FSHR) is expressed not only in granulosa cells of ovary but also in ovarian surface epithelium (OSE) and in benign and malignant epithelial ovarian tumors. The significance of this expression has remained unexplained so far. This transmembrane receptor is involved in G protein linked signal transduction and causation of neo-plasia. These finding...

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Expression of follicle-stimulating hormone receptor (FSHR) mRNA in the ovary of Zi geese during developmental and egg laying stages.

In order to evaluate the expression profile of follicle-stimulating hormone receptor (FSHR) mRNA in the ovary of Zi geese during developmental and egg laying stages, the expression levels of FSHR mRNA in the ovary of Zi geese at the ages of 1 day, 1, 2, 3, 4, 5 and 8 months (n=8, respectively) were examined by quantitative real-time PCR (qRT-PCR). The results showed that FSHR mRNA expression wa...

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ژورنال

عنوان ژورنال: Indian Journal of Science and Technology

سال: 2011

ISSN: 0974-6846,0974-5645

DOI: 10.17485/ijst/2011/v4is.51